PDB 4xxd

PDB Information

PDB4XXD
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Molecular basis for mid-region amyloid-beta capture by leading Alzheimer's disease immunotherapies.
Crespi, G.A., Hermans, S.J., Parker, M.W., Miles, L.A.
Sci Rep
HeaderImmune System
Released2015-01-30
Resolution2.410
CATH Insert Date28 Jun, 2015

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Rejected
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped
F 29 Jun, 2015 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4xxdA01 05 Jul, 2016 2.60.40.10 Assigned
4xxdA02 05 Jul, 2016 2.60.40.10 Assigned
4xxdB01 22 Jul, 2015 2.60.40.10 Assigned
4xxdB02 22 Jul, 2015 2.60.40.10 Assigned
4xxdD01 05 Jul, 2016 2.60.40.10 Assigned
4xxdD02 05 Jul, 2016 2.60.40.10 Assigned
4xxdE01 22 Jul, 2015 2.60.40.10 Assigned
4xxdE02 22 Jul, 2015 2.60.40.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein
P01857 IGHG1_HUMAN Homo sapiens Immunoglobulin heavy constant gamma 1
P01834 IGKC_HUMAN Homo sapiens Immunoglobulin kappa constant
P05067 A4_HUMAN Homo sapiens Amyloid-beta precursor protein
P01834 IGKC_HUMAN Homo sapiens Immunoglobulin kappa constant
P01857 IGHG1_HUMAN Homo sapiens Immunoglobulin heavy constant gamma 1