PDB 4xu0

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Overview

PDB Information

PDB	4XU0
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	Targeting Mycobacterium tuberculosis Biotin Protein Ligase (MtBPL) with Nucleoside-Based Bisubstrate Adenylation Inhibitors. Bockman, M.R., Kalinda, A.S., Petrelli, R., De la Mora-Rey, T., Tiwari, D., Liu, F., Dawadi, S., Nandakumar, M., Rhee, K.Y., Schnappinger, D., Finzel, B.C., Aldrich, C.C. J.Med.Chem.
Header	Ligase/Ligase Inhibitor
Released	2015-01-24
Resolution	1.600
CATH Insert Date	20 Sep, 2015

PDB Images (7)

Image of CATH 4xu0

4xu0

PDB 4xu0

Image of CATH 4xu0A

4xu0A

PDB Chain 4xu0A

Image of CATH 4xu0B

4xu0B

PDB Chain 4xu0B

Image of CATH 4xu0A01

4xu0A01

CATH Domain 4xu0A01

Image of CATH 4xu0A02

4xu0A02

CATH Domain 4xu0A02

Image of CATH 4xu0B01

4xu0B01

CATH Domain 4xu0B01

Image of CATH 4xu0B02

4xu0B02

CATH Domain 4xu0B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Sep, 2015	Chopped
B	21 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xu0A01	30 Sep, 2015	3.30.930.10	Assigned
4xu0A02	30 Sep, 2015	2.30.30.100	Assigned
4xu0B01	30 Sep, 2015	3.30.930.10	Assigned
4xu0B02	30 Sep, 2015	2.30.30.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)