PDB 4xtu

PDB Links
Overview

PDB Information

PDB	4XTU
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Mycobacterium tuberculosis
Primary Citation	Mycobacterium tuberculosis biotin ligase complexed with bisubstrate inhibitor (N-({[(1R,2S,3R,4R)-4-(6-amino-9H-purin-9-yl)-2,3-dihydroxycyclopentyl]methyl}sulfamoyl)-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide) Bockman, M.R., Kalinda, A.S., Petrelli, R., De la Mora-Rey, T., Tawari, D., Liu, F., Schnappinger, D., Finzel, B.C., Aldrich, C.C. To be Published
Header	Ligase/Ligase Inhibitor
Released	2015-01-24
Resolution	1.650
CATH Insert Date	10 Apr, 2016

PDB Images (7)

Image of CATH 4xtu

4xtu

PDB 4xtu

Image of CATH 4xtuA

4xtuA

PDB Chain 4xtuA

Image of CATH 4xtuB

4xtuB

PDB Chain 4xtuB

Image of CATH 4xtuA01

4xtuA01

CATH Domain 4xtuA01

Image of CATH 4xtuA02

4xtuA02

CATH Domain 4xtuA02

Image of CATH 4xtuB01

4xtuB01

CATH Domain 4xtuB01

Image of CATH 4xtuB02

4xtuB02

CATH Domain 4xtuB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Apr, 2016	Chopped
B	11 Apr, 2016	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xtuA01	30 Apr, 2016	3.30.930.10	Assigned
4xtuA02	30 Apr, 2016	2.30.30.100	Assigned
4xtuB01	30 Apr, 2016	3.30.930.10	Assigned
4xtuB02	30 Apr, 2016	2.30.30.100	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)
I6YFP0	I6YFP0_MYCTU	Mycobacterium tuberculosis H37Rv	Possible bifunctional protein BirA: biotin operon repressor + biotin--[acetyl-CoA-carboxylase] synthetase (Biotin--protein ligase)