PDB 4xs3

PDB Information

PDB4XS3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
Wu, F., Jiang, H., Zheng, B., Kogiso, M., Yao, Y., Zhou, C., Li, X.N., Song, Y.
J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-01-21
Resolution3.290
CATH Insert Date14 Aug, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped
B 15 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4xs3A00 01 Sep, 2016 3.40.718.10 Assigned
4xs3B00 01 Sep, 2016 3.40.718.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic