PDB 4xj0

PDB Links
Overview

PDB Information

PDB	4XJ0
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of highly potent, selective, and efficacious small molecule inhibitors of ERK1/2. Ren, L., Grina, J., Moreno, D., Blake, J.F., Gaudino, J.J., Garrey, R., Metcalf, A.T., Burkard, M., Martinson, M., Rasor, K., Chen, H., Dean, B., Gould, S.E., Pacheco, P., Shahidi-Latham, S., Yin, J., West, K., Wang, W., Moffat, J.G., Schwarz, J.B. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2015-01-08
Resolution	2.580
CATH Insert Date	27 Sep, 2015

PDB Images (7)

Image of CATH 4xj0

4xj0

PDB 4xj0

Image of CATH 4xj0A

4xj0A

PDB Chain 4xj0A

Image of CATH 4xj0B

4xj0B

PDB Chain 4xj0B

Image of CATH 4xj0A01

4xj0A01

CATH Domain 4xj0A01

Image of CATH 4xj0A02

4xj0A02

CATH Domain 4xj0A02

Image of CATH 4xj0B01

4xj0B01

CATH Domain 4xj0B01

Image of CATH 4xj0B02

4xj0B02

CATH Domain 4xj0B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Sep, 2015	Chopped
B	28 Sep, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xj0A01	30 Sep, 2015	3.30.200.20	Assigned
4xj0A02	30 Sep, 2015	1.10.510.10	Assigned
4xj0B01	01 Oct, 2015	3.30.200.20	Assigned
4xj0B02	01 Oct, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P28482	MK01_HUMAN	Homo sapiens	Mitogen-activated protein kinase 1
P28482	MK01_HUMAN	Homo sapiens	Mitogen-activated protein kinase 1