PDB 4xbc

PDB Information

PDB4XBC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceNorwalk virus (strain GI/Human/United States/Norwalk/1968)
Primary Citation
Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure-Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies.
Galasiti Kankanamalage, A.C., Kim, Y., Weerawarna, P.M., Uy, R.A., Damalanka, V.C., Mandadapu, S.R., Alliston, K.R., Mehzabeen, N., Battaile, K.P., Lovell, S., Chang, K.O., Groutas, W.C.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-12-16
Resolution1.600
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4xbcA01 22 Jul, 2015 2.40.10.10 Assigned
4xbcA02 22 Jul, 2015 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q83883 POLG_NVN68 Norovirus Hu/1968/US Genome polyprotein
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