PDB 4x48

PDB Information

PDB4X48
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
The Discovery and Characterization of the alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Potentiator N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242).
Shaffer, C.L., Patel, N.C., Schwarz, J., Scialis, R.J., Wei, Y., Hou, X.J., Xie, L., Karki, K., Bryce, D.K., Osgood, S.M., Hoffmann, W.E., Lazzaro, J.T., Chang, C., McGinnis, D.F., Lotarski, S.M., Liu, J., Obach, R.S., Weber, M.L., Chen, L., Zasadny, K.R., Seymour, P.A., Schmidt, C.J., Hajos, M., Hurst, R.S., Pandit, J., O'Donnell, C.J.
J.Med.Chem.
HeaderMembrane Protein
Released2014-12-02
Resolution1.890
CATH Insert Date28 Jun, 2015

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4x48A01 22 Jul, 2015 3.40.190.10 Assigned
4x48A02 22 Jul, 2015 3.40.190.10 Assigned
4x48B01 22 Jul, 2015 3.40.190.10 Assigned
4x48B02 22 Jul, 2015 3.40.190.10 Assigned
4x48C01 22 Jul, 2015 3.40.190.10 Assigned
4x48C02 22 Jul, 2015 3.40.190.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2
P19491 GRIA2_RAT Rattus norvegicus Glutamate receptor 2