PDB 4x48

PDB Links
Overview

PDB Information

PDB	4X48
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Rattus norvegicus
Primary Citation	The Discovery and Characterization of the alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Potentiator N-{(3S,4S)-4-[4-(5-Cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242). Shaffer, C.L., Patel, N.C., Schwarz, J., Scialis, R.J., Wei, Y., Hou, X.J., Xie, L., Karki, K., Bryce, D.K., Osgood, S.M., Hoffmann, W.E., Lazzaro, J.T., Chang, C., McGinnis, D.F., Lotarski, S.M., Liu, J., Obach, R.S., Weber, M.L., Chen, L., Zasadny, K.R., Seymour, P.A., Schmidt, C.J., Hajos, M., Hurst, R.S., Pandit, J., O'Donnell, C.J. J.Med.Chem.
Header	Membrane Protein
Released	2014-12-02
Resolution	1.890
CATH Insert Date	28 Jun, 2015

PDB Images (10)

Image of CATH 4x48

4x48

PDB 4x48

Image of CATH 4x48A

4x48A

PDB Chain 4x48A

Image of CATH 4x48B

4x48B

PDB Chain 4x48B

Image of CATH 4x48C

4x48C

PDB Chain 4x48C

Image of CATH 4x48A01

4x48A01

CATH Domain 4x48A01

Image of CATH 4x48A02

4x48A02

CATH Domain 4x48A02

Image of CATH 4x48B01

4x48B01

CATH Domain 4x48B01

Image of CATH 4x48B02

4x48B02

CATH Domain 4x48B02

Image of CATH 4x48C01

4x48C01

CATH Domain 4x48C01

Image of CATH 4x48C02

4x48C02

CATH Domain 4x48C02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4x48A01	22 Jul, 2015	3.40.190.10	Assigned
4x48A02	22 Jul, 2015	3.40.190.10	Assigned
4x48B01	22 Jul, 2015	3.40.190.10	Assigned
4x48B02	22 Jul, 2015	3.40.190.10	Assigned
4x48C01	22 Jul, 2015	3.40.190.10	Assigned
4x48C02	22 Jul, 2015	3.40.190.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2
P19491	GRIA2_RAT	Rattus norvegicus	Glutamate receptor 2