PDB 4x2i

PDB Information

PDB4X2I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.
Taylor, A.M., Vaswani, R.G., Gehling, V.S., Hewitt, M.C., Leblanc, Y., Audia, J.E., Bellon, S., Cummings, R.T., Cote, A., Harmange, J.C., Jayaram, H., Joshi, S., Lora, J.M., Mertz, J.A., Neiss, A., Pardo, E., Nasveschuk, C.G., Poy, F., Sandy, P., Setser, J.W., Sims, R.J., Tang, Y., Albrecht, B.K.
Acs Med.Chem.Lett.
HeaderSignaling Protein
Released2014-11-26
Resolution1.200
CATH Insert Date29 Nov, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4x2iA01 02 Dec, 2015 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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