PDB 4x1k

PDB Information

PDB4X1K
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
Maderna, A., Doroski, M., Subramanyam, C., Porte, A., Leverett, C.A., Vetelino, B.C., Chen, Z., Risley, H., Parris, K., Pandit, J., Varghese, A.H., Shanker, S., Song, C., Sukuru, S.C., Farley, K.A., Wagenaar, M.M., Shapiro, M.J., Musto, S., Lam, M.H., Loganzo, F., O'Donnell, C.J.
J.Med.Chem.
HeaderStructural Protein/Inhibitor
Released2014-11-24
Resolution3.500
CATH Insert Date28 Jun, 2015

PDB Images (19)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped

CATH Domains (13)

Domain ID Date inserted into CATH Superfamily CATH Status
4x1kA01 22 Jul, 2015 3.40.50.1440 Assigned
4x1kA02 22 Jul, 2015 3.30.1330.20 Assigned
4x1kA03 22 Jul, 2015 1.10.287.600 Assigned
4x1kB01 22 Jul, 2015 3.40.50.1440 Assigned
4x1kB02 22 Jul, 2015 3.30.1330.20 Assigned
4x1kB03 22 Jul, 2015 1.10.287.600 Assigned
4x1kC01 22 Jul, 2015 3.40.50.1440 Assigned
4x1kC02 22 Jul, 2015 3.30.1330.20 Assigned
4x1kC03 22 Jul, 2015 1.10.287.600 Assigned
4x1kD01 22 Jul, 2015 3.40.50.1440 Assigned
4x1kD02 22 Jul, 2015 3.30.1330.20 Assigned
4x1kD03 22 Jul, 2015 1.10.287.600 Assigned
4x1kE01 22 Jul, 2015 6.10.280.30 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain