PDB 4x1i

PDB Information

PDB4X1I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
Discovery of cytotoxic dolastatin 10 analogues with N-terminal modifications.
Maderna, A., Doroski, M., Subramanyam, C., Porte, A., Leverett, C.A., Vetelino, B.C., Chen, Z., Risley, H., Parris, K., Pandit, J., Varghese, A.H., Shanker, S., Song, C., Sukuru, S.C., Farley, K.A., Wagenaar, M.M., Shapiro, M.J., Musto, S., Lam, M.H., Loganzo, F., O'Donnell, C.J.
J.Med.Chem.
HeaderStructural Protein/Inhibitor
Released2014-11-24
Resolution3.110
CATH Insert Date28 Jun, 2015

PDB Images (19)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped

CATH Domains (13)

Domain ID Date inserted into CATH Superfamily CATH Status
4x1iA01 20 Jul, 2015 3.40.50.1440 Assigned
4x1iA02 20 Jul, 2015 3.30.1330.20 Assigned
4x1iA03 20 Jul, 2015 1.10.287.600 Assigned
4x1iB01 22 Jul, 2015 3.40.50.1440 Assigned
4x1iB02 22 Jul, 2015 3.30.1330.20 Assigned
4x1iB03 22 Jul, 2015 1.10.287.600 Assigned
4x1iC01 22 Jul, 2015 3.40.50.1440 Assigned
4x1iC02 22 Jul, 2015 3.30.1330.20 Assigned
4x1iC03 22 Jul, 2015 1.10.287.600 Assigned
4x1iD01 22 Jul, 2015 3.40.50.1440 Assigned
4x1iD02 22 Jul, 2015 3.30.1330.20 Assigned
4x1iD03 22 Jul, 2015 1.10.287.600 Assigned
4x1iE01 20 Jul, 2015 6.10.280.30 Assigned

UniProtKB Entries (5)

Accession Gene ID Taxon Description
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWY9 D0VWY9_SHEEP Ovis aries Tubulin beta chain
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
D0VWZ0 D0VWZ0_SHEEP Ovis aries Tubulin alpha chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4