PDB 4wvt

PDB Information

PDB4WVT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The Discovery of Macrocyclic XIAP Antagonists from a DNA-Programmed Chemistry Library, and Their Optimization To Give Lead Compounds with in Vivo Antitumor Activity.
Seigal, B.A., Connors, W.H., Fraley, A., Borzilleri, R.M., Carter, P.H., Emanuel, S.L., Fargnoli, J., Kim, K., Lei, M., Naglich, J.G., Pokross, M.E., Posy, S.L., Shen, H., Surti, N., Talbott, R., Zhang, Y., Terrett, N.K.
J.Med.Chem.
HeaderApoptosis
Released2014-11-07
Resolution1.960
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Rejected
D 29 Jun, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4wvtA00 22 Jul, 2015 1.10.1170.10 Assigned
4wvtB00 22 Jul, 2015 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
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