PDB Information

PDB4WV5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The novolactone natural product disrupts the allosteric regulation of hsp70.
Hassan, A.Q., Kirby, C.A., Zhou, W., Schuhmann, T., Kityk, R., Kipp, D.R., Baird, J., Chen, J., Chen, Y., Chung, F., Hoepfner, D., Movva, N.R., Pagliarini, R., Petersen, F., Quinn, C., Quinn, D., Riedl, R., Schmitt, E.K., Schitter, A., Stams, T., Studer, C., Fortin, P.D., Mayer, M.P., Sadlish, H.
Chem.Biol.
HeaderChaperone
Released2014-11-04
Resolution2.040
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4wv5A00 22 Jul, 2015 2.60.34.10 Assigned
4wv5B00 22 Jul, 2015 2.60.34.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0DMV9 HS71B_HUMAN Homo sapiens Heat shock 70 kDa protein 1B
P0DMV9 HS71B_HUMAN Homo sapiens Heat shock 70 kDa protein 1B