PDB 4waf

PDB Links
Overview

PDB Information

PDB	4WAF
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]pyrazines as ATR Inhibitors. Barsanti, P.A., Aversa, R.J., Jin, X., Pan, Y., Lu, Y., Elling, R., Jain, R., Knapp, M., Lan, J., Lin, X., Rudewicz, P., Sim, J., Taricani, L., Thomas, G., Xiao, L., Yue, Q. Acs Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2014-08-29
Resolution	2.390
CATH Insert Date	04 Jan, 2015

PDB Images (10)

Image of CATH 4waf

4waf

PDB 4waf

Image of CATH 4wafA

4wafA

PDB Chain 4wafA

Image of CATH 4wafB

4wafB

PDB Chain 4wafB

Image of CATH 4wafA01

4wafA01

CATH Domain 4wafA01

Image of CATH 4wafA02

4wafA02

CATH Domain 4wafA02

Image of CATH 4wafA03

4wafA03

CATH Domain 4wafA03

Image of CATH 4wafA04

4wafA04

CATH Domain 4wafA04

Image of CATH 4wafA05

4wafA05

CATH Domain 4wafA05

Image of CATH 4wafB01

4wafB01

CATH Domain 4wafB01

Image of CATH 4wafB02

4wafB02

CATH Domain 4wafB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Jan, 2015	Chopped
B	05 Jan, 2015	Chopped

CATH Domains (7)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4wafA01	08 Jan, 2015	3.10.20.770	Assigned
4wafA02	08 Jan, 2015	2.60.40.150	Assigned
4wafA03	08 Jan, 2015	1.25.40.70	Assigned
4wafA04	08 Jan, 2015	3.30.1010.10	Assigned
4wafA05	08 Jan, 2015	1.10.1070.11	Assigned
4wafB01	14 Nov, 2017		Holding pen
4wafB02	14 Nov, 2017	1.10.287.1490	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27986	P85A_HUMAN	Homo sapiens	Phosphatidylinositol 3-kinase regulatory subunit alpha
P42336	PK3CA_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform