PDB 4w7p

PDB Information

PDB4W7P
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Novel ROCK inhibitors for the treatment of pulmonary arterial hypertension.
Shaw, D., Hollingworth, G., Soldermann, N., Sprague, E., Schuler, W., Vangrevelinghe, E., Duggan, N., Thomas, M., Kosaka, T., Waters, N., van Eis, M.J.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-08-22
Resolution2.800
CATH Insert Date26 Oct, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 27 Oct, 2014 Chopped
B 27 Oct, 2014 Chopped
C 27 Oct, 2014 Chopped
D 27 Oct, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4w7pA01 07 Mar, 2018 3.30.200.20 Assigned
4w7pA02 07 Mar, 2018 1.10.510.10 Assigned
4w7pB01 07 Mar, 2018 3.30.200.20 Assigned
4w7pB02 07 Mar, 2018 1.10.510.10 Assigned
4w7pC01 07 Mar, 2018 3.30.200.20 Assigned
4w7pC02 07 Mar, 2018 1.10.510.10 Assigned
4w7pD01 07 Mar, 2018 3.30.200.20 Assigned
4w7pD02 07 Mar, 2018 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
Q13464 ROCK1_HUMAN Homo sapiens Rho-associated protein kinase 1
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