PDB 4w5s

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Overview

PDB Information

PDB	4W5S
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology. Johannes, J.W., Almeida, L., Barlaam, B., Boriack-Sjodin, P.A., Casella, R., Croft, R.A., Dishington, A.P., Gingipalli, L., Gu, C., Hawkins, J.L., Holmes, J.L., Howard, T., Huang, J., Ioannidis, S., Kazmirski, S., Lamb, M.L., McGuire, T.M., Moore, J.E., Ogg, D., Patel, A., Pike, K.G., Pontz, T., Robb, G.R., Su, N., Wang, H., Wu, X., Zhang, H.J., Zhang, Y., Zheng, X., Wang, T. Acs Med.Chem.Lett.
Header	Transferase/Inhibitor
Released	2014-08-18
Resolution	2.800
CATH Insert Date	28 Jun, 2015

PDB Images (3)

Image of CATH 4w5s

4w5s

PDB 4w5s

Image of CATH 4w5sA

4w5sA

PDB Chain 4w5sA

Image of CATH 4w5sA00

4w5sA00

CATH Domain 4w5sA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4w5sA00	15 Jul, 2015	3.90.228.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
O95271	TNKS1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-1