PDB Information

PDB4V05
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Structural Insights Into Fgfr Kinase Isoform Selectivity: Diverse Binding Modes of Azd4547 and Ponatinib in Complex with Fgfr1 and Fgfr4
Tucker, J.A., Klein, T., Breed, J., Breeze, A.L., Overman, R., Phillips, C., Norman, R.A.
Structure
HeaderTransferase
Released2014-09-10
Resolution2.570
CATH Insert Date21 Dec, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4v05A01 29 Dec, 2014 3.30.200.20 Assigned
4v05A02 29 Dec, 2014 1.10.510.10 Assigned
4v05B01 29 Dec, 2014 3.30.200.20 Assigned
4v05B02 29 Dec, 2014 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
D3DSX2 D3DSX2_HUMAN Homo sapiens Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b
D3DSX2 D3DSX2_HUMAN Homo sapiens Fibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b