PDB 4uyh

PDB Links
Overview

PDB Information

PDB	4UYH
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	The Discovery of I-Bet726 (Gsk1324726A), a Potent Tetrahydroquinoline Apoa1 Up-Regulator and Selective Bet Bromodomain Inhibitor. Gosmini, R., Nguyen, V.L., Toum, J., Simon, C., Brusq, J.M., Krysa, G., Mirguet, O., Riou-Eymard, A.M., Boursier, E.V., Trottet, L., Bamborough, P., Clark, H., Chung, C.W., Cutler, L., Demont, E.H., Kaur, R., Lewis, A.J., Schilling, M.B., Soden, P.E., Taylor, S., Walker, A.L., Walker, M.D., Prinjha, R.K., Nicodeme, E. J.Med.Chem.
Header	Transcription
Released	2014-08-31
Resolution	1.730
CATH Insert Date	19 Oct, 2014

PDB Images (7)

Image of CATH 4uyh

4uyh

PDB 4uyh

Image of CATH 4uyhA

4uyhA

PDB Chain 4uyhA

Image of CATH 4uyhB

4uyhB

PDB Chain 4uyhB

Image of CATH 4uyhC

4uyhC

PDB Chain 4uyhC

Image of CATH 4uyhA00

4uyhA00

CATH Domain 4uyhA00

Image of CATH 4uyhB00

4uyhB00

CATH Domain 4uyhB00

Image of CATH 4uyhC00

4uyhC00

CATH Domain 4uyhC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Oct, 2014	Chopped
B	20 Oct, 2014	Chopped
C	20 Oct, 2014	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4uyhA00	21 Oct, 2014	1.20.920.10	Assigned
4uyhB00	21 Oct, 2014	1.20.920.10	Assigned
4uyhC00	21 Oct, 2014	1.20.920.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2