PDB 4uxl

PDB Information

PDB4UXL
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Pf-06463922 is a Potent and Selective Next-Generation Ros1/Alk Inhibitor Capable of Blocking Crizotinib-Resistant Ros1 Mutations.
Zou, H.Y., Li, Q., Engstrom, L.D., West, M., Appleman, V., Wong, K.A., Mctigue, M., Deng, Y., Liu, W., Brooun, A., Timofeevski, S., Mcdonnell, S.R.P., Jiang, P., Falk, M.D., Lappin, P.B., Affolter, T., Nichols, T., Hu, W., Lam, J., Johnson, T.W., Smeal, T., Charest, A., Fantin, V.R.
Proc.Natl.Acad.Sci.USA
HeaderTransferase
Released2014-08-25
Resolution2.400
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4uxlA01 15 Jul, 2015 3.30.200.20 Assigned
4uxlA02 15 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08922 ROS1_HUMAN Homo sapiens Proto-oncogene tyrosine-protein kinase ROS