PDB Information

PDB4UVX
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI BL21(DE3)
Gene SourceHOMO SAPIENS
Primary Citation
Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro.
Paine, H.A., Nathubhai, A., Woon, E.C.Y., Sunderland, P.T., Wood, P.J., Mahon, M.F., Lloyd, M.D., Thompson, A.S., Haikarainen, T., Narwal, M., Lehtio, L., Threadgill, M.D.
Bioorg.Med.Chem.
HeaderTransferase
Released2014-08-08
Resolution1.950
CATH Insert Date16 Aug, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Aug, 2015 Chopped
B 17 Aug, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4uvxA00 24 Aug, 2015 3.90.228.10 Assigned
4uvxB00 24 Aug, 2015 3.90.228.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Tankyrase-2