PDB 4ui5

PDB Information

PDB4UI5
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Structure-Activity Relationships of 2-Arylquinazolin-4-Ones as Highly Selective and Potent Inhibitors of the Tankyrases.
Nathubhai, A., Haikarainen, T., Hayward, P.C., Munoz-Descalzo, S., Thompson, A.S., Lloyd, M.D., Lehtio, L., Threadgill, M.D.
Eur.J.Med.Chem.
HeaderTransferase
Released2015-03-27
Resolution1.650
CATH Insert Date24 Apr, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 25 Apr, 2016 Chopped
B 25 Apr, 2016 Chopped
C 25 Apr, 2016 Chopped
D 25 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ui5A00 29 Apr, 2016 3.90.228.10 Assigned
4ui5B00 29 Apr, 2016 3.90.228.10 Assigned
4ui5C00 29 Apr, 2016 6.20.320.10 Assigned
4ui5D00 29 Apr, 2016 6.20.320.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2 TNKS2_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-2