PDB 4u8w

PDB Information

PDB4U8W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1 BH10
Primary Citation
Design of gem-Difluoro-bis-Tetrahydrofuran as P2 Ligand for HIV-1 Protease Inhibitors to Improve Brain Penetration: Synthesis, X-ray Studies, and Biological Evaluation.
Ghosh, A.K., Yashchuk, S., Mizuno, A., Chakraborty, N., Agniswamy, J., Wang, Y.F., Aoki, M., Gomez, P.M., Amano, M., Weber, I.T., Mitsuya, H.
Chemmedchem
HeaderHydrolase/Hydrolase Inhibitor
Released2014-08-05
Resolution1.300
CATH Insert Date16 Nov, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 17 Nov, 2014 Chopped
B 17 Nov, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4u8wA00 19 Nov, 2014 2.40.70.10 Assigned
4u8wB00 19 Nov, 2014 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein