PDB 4u43

PDB Links
Overview

PDB Information

PDB	4U43
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors. Wang, L., Stanley, M., Boggs, J.W., Crawford, T.D., Bravo, B.J., Giannetti, A.M., Harris, S.F., Magnuson, S.R., Nonomiya, J., Schmidt, S., Wu, P., Ye, W., Gould, S.E., Murray, L.J., Ndubaku, C.O., Chen, H. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2014-07-23
Resolution	2.180
CATH Insert Date	14 Sep, 2014

PDB Images (7)

Image of CATH 4u43

4u43

PDB 4u43

Image of CATH 4u43A

4u43A

PDB Chain 4u43A

Image of CATH 4u43B

4u43B

PDB Chain 4u43B

Image of CATH 4u43A01

4u43A01

CATH Domain 4u43A01

Image of CATH 4u43A02

4u43A02

CATH Domain 4u43A02

Image of CATH 4u43B01

4u43B01

CATH Domain 4u43B01

Image of CATH 4u43B02

4u43B02

CATH Domain 4u43B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 Sep, 2014	Chopped
B	15 Sep, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4u43A01	16 Sep, 2014	3.30.200.20	Assigned
4u43A02	16 Sep, 2014	1.10.510.10	Assigned
4u43B01	16 Sep, 2014	3.30.200.20	Assigned
4u43B02	16 Sep, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4