PDB 4ty6

PDB Information

PDB4TY6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Phenylimidazoles as Potent and Selective Inhibitors of Coagulation Factor XIa with in Vivo Antithrombotic Activity.
Hangeland, J.J., Friends, T.J., Rossi, K.A., Smallheer, J.M., Wang, C., Sun, Z., Corte, J.R., Fang, T., Wong, P.C., Rendina, A.R., Barbera, F.A., Bozarth, J.M., Luettgen, J.M., Watson, C.A., Zhang, G., Wei, A., Ramamurthy, V., Morin, P.E., Bisacchi, G.S., Subramaniam, S., Arunachalam, P., Mathur, A., Seiffert, D.A., Wexler, R.R., Quan, M.L.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-07-07
Resolution1.850
CATH Insert Date21 Dec, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
H 22 Dec, 2014 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ty6A01 28 Dec, 2014 2.40.10.10 Assigned
4ty6A02 28 Dec, 2014 2.40.10.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI
P03951 FA11_HUMAN Homo sapiens Coagulation factor XI