PDB 4tv8

PDB Information

PDB4TV8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Proc.Natl.Acad.Sci.USA
HeaderCell Cycle
Released2014-06-26
Resolution2.100
CATH Insert Date07 Sep, 2014

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 08 Sep, 2014 Chopped
B 08 Sep, 2014 Chopped
C 08 Sep, 2014 Chopped
D 08 Sep, 2014 Chopped
E 08 Sep, 2014 Chopped
F 08 Sep, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4tv8A01 10 Sep, 2014 3.40.50.1440 Assigned
4tv8A02 10 Sep, 2014 3.30.1330.20 Assigned
4tv8A03 10 Sep, 2014 1.10.287.600 Assigned
4tv8B01 10 Sep, 2014 3.40.50.1440 Assigned
4tv8B02 10 Sep, 2014 3.30.1330.20 Assigned
4tv8B03 10 Sep, 2014 1.10.287.600 Assigned
4tv8C01 10 Sep, 2014 3.40.50.1440 Assigned
4tv8C02 10 Sep, 2014 3.30.1330.20 Assigned
4tv8C03 10 Sep, 2014 1.10.287.600 Assigned
4tv8D01 10 Sep, 2014 3.40.50.1440 Assigned
4tv8D02 10 Sep, 2014 3.30.1330.20 Assigned
4tv8D03 10 Sep, 2014 1.10.287.600 Assigned
4tv8E01 10 Sep, 2014 6.10.280.30 Assigned
4tv8F01 10 Sep, 2014 3.40.50.11480 Assigned
4tv8F02 10 Sep, 2014 3.30.470.20 Assigned
4tv8F03 10 Sep, 2014 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
P63043 STMN4_RAT Rattus norvegicus Stathmin-4