PDB 4tuh

PDB Information

PDB4TUH
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Rescaffolding of Selective Antagonists of BCL-XL.
Koehler, M.F., Bergeron, P., Choo, E.F., Lau, K., Ndubaku, C., Dudley, D., Gibbons, P., Sleebs, B.E., Rye, C.S., Nikolakopoulos, G., Bui, C., Kulasegaram, S., Kersten, W.J., Smith, B.J., Czabotar, P.E., Colman, P.M., Huang, D.C., Baell, J.B., Watson, K.G., Hasvold, L., Tao, Z.F., Wang, L., Souers, A.J., Elmore, S.W., Flygare, J.A., Fairbrother, W.J., Lessene, G.
Acs Med.Chem.Lett.
HeaderApoptosis
Released2014-06-24
Resolution1.800
CATH Insert Date26 Oct, 2014

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 27 Oct, 2014 Chopped
B 27 Oct, 2014 Chopped
C 27 Oct, 2014 Chopped
D 27 Oct, 2014 Chopped
E 27 Oct, 2014 Chopped
F 27 Oct, 2014 Chopped
G 27 Oct, 2014 Chopped
H 27 Oct, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4tuhA01 02 Nov, 2014 Holding pen
4tuhB01 02 Nov, 2014 Holding pen
4tuhC01 02 Nov, 2014 Holding pen
4tuhD01 02 Nov, 2014 Holding pen
4tuhE01 02 Nov, 2014 Holding pen
4tuhF01 02 Nov, 2014 Holding pen
4tuhG01 02 Nov, 2014 Holding pen
4tuhH01 02 Nov, 2014 Holding pen

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1
Q07817 B2CL1_HUMAN Homo sapiens Bcl-2-like protein 1