PDB 4s1g

PDB Information

PDB4S1G
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Iminopyrimidinones: A novel pharmacophore for the development of orally active renin inhibitors.
McKittrick, B.A., Caldwell, J.P., Bara, T., Boykow, G., Chintala, M., Clader, J., Czarniecki, M., Courneya, B., Duffy, R., Fleming, L., Giessert, R., Greenlee, W.J., Heap, C., Hong, L., Huang, Y., Iserloh, U., Josien, H., Khan, T., Korfmacher, W., Liang, X., Mazzola, R., Mitra, S., Moore, K., Orth, P., Rajagopalan, M., Roy, S., Sakwa, S., Strickland, C., Vaccaro, H., Voigt, J., Wang, H., Wong, J., Zhang, R., Zych, A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-01-13
Resolution2.100
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4s1gA01 15 Jul, 2015 2.40.70.10 Assigned
4s1gA02 15 Jul, 2015 2.40.70.10 Assigned
4s1gB01 13 Jul, 2015 2.40.70.10 Assigned
4s1gB02 13 Jul, 2015 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin