PDB Information

PDB4RYC
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceHomo sapiens
Primary Citation
trans-(3S,4S)-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part I: Prime site exploration using an amino linker.
Lorthiois, E., Cumin, F., Ehrhardt, C., Kosaka, T., Sellner, H., Ostermann, N., Francotte, E., Wagner, T., Maibaum, J.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-12-15
Resolution2.450
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4rycA01 10 Jul, 2015 2.40.70.10 Assigned
4rycA02 10 Jul, 2015 2.40.70.10 Assigned
4rycB01 10 Jul, 2015 2.40.70.10 Assigned
4rycB02 10 Jul, 2015 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin