PDB 4rv6

PDB Information

PDB4RV6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.
Thorsell, A.G., Ekblad, T., Karlberg, T., Low, M., Pinto, A.F., Tresaugues, L., Moche, M., Cohen, M.S., Schuler, H.
J. Med. Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-11-25
Resolution3.190
CATH Insert Date20 Dec, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Dec, 2015 Chopped
B 21 Dec, 2015 Chopped
C 21 Dec, 2015 Chopped
D 21 Dec, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4rv6A01 05 Jan, 2016 1.20.142.10 Assigned
4rv6A02 05 Jan, 2016 3.90.228.10 Assigned
4rv6B01 05 Jan, 2016 1.20.142.10 Assigned
4rv6B02 05 Jan, 2016 3.90.228.10 Assigned
4rv6C01 05 Jan, 2016 1.20.142.10 Assigned
4rv6C02 05 Jan, 2016 3.90.228.10 Assigned
4rv6D01 05 Jan, 2016 1.20.142.10 Assigned
4rv6D02 05 Jan, 2016 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
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