PDB 4rmj

PDB Links
Overview

PDB Information

PDB	4RMJ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Selective Sirt2 inhibition by ligand-induced rearrangement of the active site. Rumpf, T., Schiedel, M., Karaman, B., Roessler, C., North, B.J., Lehotzky, A., Olah, J., Ladwein, K.I., Schmidtkunz, K., Gajer, M., Pannek, M., Steegborn, C., Sinclair, D.A., Gerhardt, S., Ovadi, J., Schutkowski, M., Sippl, W., Einsle, O., Jung, M. Nat Commun
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-10-21
Resolution	1.870
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4rmj

4rmj

PDB 4rmj

Image of CATH 4rmjA

4rmjA

PDB Chain 4rmjA

Image of CATH 4rmjB

4rmjB

PDB Chain 4rmjB

Image of CATH 4rmjA01

4rmjA01

CATH Domain 4rmjA01

Image of CATH 4rmjA02

4rmjA02

CATH Domain 4rmjA02

Image of CATH 4rmjB01

4rmjB01

CATH Domain 4rmjB01

Image of CATH 4rmjB02

4rmjB02

CATH Domain 4rmjB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4rmjA01	10 Jul, 2015	3.40.50.1220	Assigned
4rmjA02	10 Jul, 2015	3.30.1600.10	Assigned
4rmjB01	10 Jul, 2015	3.40.50.1220	Assigned
4rmjB02	10 Jul, 2015	3.30.1600.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q8IXJ6	SIR2_HUMAN	Homo sapiens	NAD-dependent protein deacetylase sirtuin-2
Q8IXJ6	SIR2_HUMAN	Homo sapiens	NAD-dependent protein deacetylase sirtuin-2