PDB 4rmg

PDB Information

PDB4RMG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.
Rumpf, T., Schiedel, M., Karaman, B., Roessler, C., North, B.J., Lehotzky, A., Olah, J., Ladwein, K.I., Schmidtkunz, K., Gajer, M., Pannek, M., Steegborn, C., Sinclair, D.A., Gerhardt, S., Ovadi, J., Schutkowski, M., Sippl, W., Einsle, O., Jung, M.
Nat Commun
HeaderHydrolase/Hydrolase Inbititor
Released2014-10-21
Resolution1.880
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rmgA01 10 Jul, 2015 3.40.50.1220 Assigned
4rmgA02 10 Jul, 2015 3.30.1600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2