PDB 4rls

PDB Information

PDB4RLS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of 3,6-disubstituted dihydropyrones as inhibitors of human lactate dehydrogenase.
Fauber, B.P., Dragovich, P.S., Chen, J., Corson, L.B., Ding, C.Z., Eigenbrot, C., Labadie, S., Malek, S., Peterson, D., Purkey, H.E., Robarge, K., Sideris, S., Ultsch, M., Wei, B., Yen, I., Yue, Q., Zhou, A.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2014-10-17
Resolution1.910
CATH Insert Date30 Nov, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 01 Dec, 2014 Chopped
B 01 Dec, 2014 Chopped
C 01 Dec, 2014 Chopped
D 01 Dec, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4rlsA01 03 Dec, 2014 3.40.50.720 Assigned
4rlsA02 03 Dec, 2014 3.90.110.10 Assigned
4rlsB01 03 Dec, 2014 3.40.50.720 Assigned
4rlsB02 03 Dec, 2014 3.90.110.10 Assigned
4rlsC01 03 Dec, 2014 3.40.50.720 Assigned
4rlsC02 03 Dec, 2014 3.90.110.10 Assigned
4rlsD01 03 Dec, 2014 3.40.50.720 Assigned
4rlsD02 03 Dec, 2014 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain