PDB Information

PDB4RIW
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutations.
Littlefield, P., Liu, L., Mysore, V., Shan, Y., Shaw, D.E., Jura, N.
Sci.Signal.
HeaderTransferase
Released2014-10-07
Resolution3.100
CATH Insert Date21 Dec, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped
C 22 Dec, 2014 Chopped
D 22 Dec, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4riwA01 29 Dec, 2014 3.30.200.20 Assigned
4riwA02 29 Dec, 2014 1.10.510.10 Assigned
4riwB01 29 Dec, 2014 3.30.200.20 Assigned
4riwB02 29 Dec, 2014 1.10.510.10 Assigned
4riwC01 29 Dec, 2014 3.30.200.20 Assigned
4riwC02 29 Dec, 2014 1.10.510.10 Assigned
4riwD01 29 Dec, 2014 3.30.200.20 Assigned
4riwD02 29 Dec, 2014 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor