PDB 4rhu

PDB Information

PDB4RHU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.
Eng, W.S., Hockova, D., Spacek, P., Janeba, Z., West, N.P., Woods, K., Naesens, L.M., Keough, D.T., Guddat, L.W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-10-03
Resolution2.570
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped
F 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4rhuA00 10 Jul, 2015 3.40.50.2020 Assigned
4rhuB00 11 Jul, 2015 3.40.50.2020 Assigned
4rhuC00 11 Jul, 2015 3.40.50.2020 Assigned
4rhuD00 11 Jul, 2015 3.40.50.2020 Assigned
4rhuE00 10 Jul, 2015 3.40.50.2020 Assigned
4rhuF00 11 Jul, 2015 3.40.50.2020 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase