PDB 4re9

PDB Information

PDB4RE9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice.
Deprez-Poulain, R., Hennuyer, N., Bosc, D., Liang, W.G., Enee, E., Marechal, X., Charton, J., Totobenazara, J., Berte, G., Jahklal, J., Verdelet, T., Dumont, J., Dassonneville, S., Woitrain, E., Gauriot, M., Paquet, C., Duplan, I., Hermant, P., Cantrelle, F.X., Sevin, E., Culot, M., Landry, V., Herledan, A., Piveteau, C., Lippens, G., Leroux, F., Tang, W.J., van Endert, P., Staels, B., Deprez, B.
Nat Commun
HeaderHydrolase/Hydrolase Inhibitor
Released2014-09-22
Resolution2.910
CATH Insert Date04 Oct, 2015

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Oct, 2015 Chopped
B 05 Oct, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4re9A01 01 Nov, 2015 3.30.830.10 Assigned
4re9A02 01 Nov, 2015 3.30.830.10 Assigned
4re9A03 01 Nov, 2015 3.30.830.10 Assigned
4re9A04 01 Nov, 2015 3.30.830.10 Assigned
4re9B01 01 Nov, 2015 3.30.830.10 Assigned
4re9B02 01 Nov, 2015 3.30.830.10 Assigned
4re9B03 01 Nov, 2015 3.30.830.10 Assigned
4re9B04 01 Nov, 2015 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme