PDB 4re9

PDB Links
Overview

PDB Information

PDB	4RE9
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Deprez-Poulain, R., Hennuyer, N., Bosc, D., Liang, W.G., Enee, E., Marechal, X., Charton, J., Totobenazara, J., Berte, G., Jahklal, J., Verdelet, T., Dumont, J., Dassonneville, S., Woitrain, E., Gauriot, M., Paquet, C., Duplan, I., Hermant, P., Cantrelle, F.X., Sevin, E., Culot, M., Landry, V., Herledan, A., Piveteau, C., Lippens, G., Leroux, F., Tang, W.J., van Endert, P., Staels, B., Deprez, B. Nat Commun
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-09-22
Resolution	2.910
CATH Insert Date	04 Oct, 2015

PDB Images (11)

Image of CATH 4re9

4re9

PDB 4re9

Image of CATH 4re9A

4re9A

PDB Chain 4re9A

Image of CATH 4re9B

4re9B

PDB Chain 4re9B

Image of CATH 4re9A01

4re9A01

CATH Domain 4re9A01

Image of CATH 4re9A02

4re9A02

CATH Domain 4re9A02

Image of CATH 4re9A03

4re9A03

CATH Domain 4re9A03

Image of CATH 4re9A04

4re9A04

CATH Domain 4re9A04

Image of CATH 4re9B01

4re9B01

CATH Domain 4re9B01

Image of CATH 4re9B02

4re9B02

CATH Domain 4re9B02

Image of CATH 4re9B03

4re9B03

CATH Domain 4re9B03

Image of CATH 4re9B04

4re9B04

CATH Domain 4re9B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Oct, 2015	Chopped
B	05 Oct, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4re9A01	01 Nov, 2015	3.30.830.10	Assigned
4re9A02	01 Nov, 2015	3.30.830.10	Assigned
4re9A03	01 Nov, 2015	3.30.830.10	Assigned
4re9A04	01 Nov, 2015	3.30.830.10	Assigned
4re9B01	01 Nov, 2015	3.30.830.10	Assigned
4re9B02	01 Nov, 2015	3.30.830.10	Assigned
4re9B03	01 Nov, 2015	3.30.830.10	Assigned
4re9B04	01 Nov, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme