PDB 4rcf

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Overview

PDB Information

PDB	4RCF
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors. Epstein, O., Bryan, M.C., Cheng, A.C., Derakhchan, K., Dineen, T.A., Hickman, D., Hua, Z., Human, J.B., Kreiman, C., Marx, I.E., Weiss, M.M., Wahl, R.C., Wen, P.H., Whittington, D.A., Wood, S., Zheng, X.M., Fremeau, R.T., White, R.D., Patel, V.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-09-15
Resolution	1.780
CATH Insert Date	04 Jan, 2015

PDB Images (4)

Image of CATH 4rcf

4rcf

PDB 4rcf

Image of CATH 4rcfA

4rcfA

PDB Chain 4rcfA

Image of CATH 4rcfA01

4rcfA01

CATH Domain 4rcfA01

Image of CATH 4rcfA02

4rcfA02

CATH Domain 4rcfA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Jan, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4rcfA01	08 Jan, 2015	2.40.70.10	Assigned
4rcfA02	08 Jan, 2015	2.40.70.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1