PDB Information

Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors.
Epstein, O., Bryan, M.C., Cheng, A.C., Derakhchan, K., Dineen, T.A., Hickman, D., Hua, Z., Human, J.B., Kreiman, C., Marx, I.E., Weiss, M.M., Wahl, R.C., Wen, P.H., Whittington, D.A., Wood, S., Zheng, X.M., Fremeau, R.T., White, R.D., Patel, V.F.
HeaderHydrolase/Hydrolase Inhibitor
CATH Insert Date04 Jan, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Jan, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rceA01 10 Jan, 2015 Assigned
4rceA02 10 Jan, 2015 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1