PDB 4r6e

PDB Information

PDB4R6E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors.
Thorsell, A.G., Ekblad, T., Karlberg, T., Low, M., Pinto, A.F., Tresaugues, L., Moche, M., Cohen, M.S., Schuler, H.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-08-25
Resolution2.200
CATH Insert Date20 Sep, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2015 Chopped
B 21 Sep, 2015 Chopped
C 21 Sep, 2015 Chopped
D 21 Sep, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4r6eA01 30 Sep, 2015 1.20.142.10 Assigned
4r6eA02 30 Sep, 2015 3.90.228.10 Assigned
4r6eB01 30 Sep, 2015 1.20.142.10 Assigned
4r6eB02 30 Sep, 2015 3.90.228.10 Assigned
4r6eC01 30 Sep, 2015 1.20.142.10 Assigned
4r6eC02 30 Sep, 2015 3.90.228.10 Assigned
4r6eD01 30 Sep, 2015 1.20.142.10 Assigned
4r6eD02 30 Sep, 2015 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
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