PDB Information

PDB4QXQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA.
Gao, P., Zillinger, T., Wang, W., Ascano, M., Dai, P., Hartmann, G., Tuschl, T., Deng, L., Barchet, W., Patel, D.J.
Cell Rep
HeaderImmune System
Released2014-07-21
Resolution2.420
CATH Insert Date14 Sep, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4qxqA01 16 Sep, 2014 New
4qxqA02 16 Sep, 2014 3.40.50.12100 Assigned
4qxqB01 16 Sep, 2014 New
4qxqB02 16 Sep, 2014 3.40.50.12100 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q86WV6 STING_HUMAN Homo sapiens Stimulator of interferon genes protein
Q86WV6 STING_HUMAN Homo sapiens Stimulator of interferon genes protein