PDB Information

PDB4QO4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2-p53 Interaction.
Yu, M., Wang, Y., Zhu, J., Bartberger, M.D., Canon, J., Chen, A., Chow, D., Eksterowicz, J., Fox, B., Fu, J., Gribble, M., Huang, X., Li, Z., Liu, J.J., Lo, M.C., McMinn, D., Oliner, J.D., Osgood, T., Rew, Y., Saiki, A.Y., Shaffer, P., Yan, X., Ye, Q., Yu, D., Zhao, X., Zhou, J., Olson, S.H., Medina, J.C., Sun, D.
ACS Med Chem Lett
HeaderLigase/Ligase Inhibitor
Released2014-06-19
Resolution1.700
CATH Insert Date27 Jul, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Jul, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4qo4A00 03 Aug, 2014 1.10.245.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q00987 MDM2_HUMAN Homo sapiens E3 ubiquitin-protein ligase Mdm2