PDB 4qia

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Overview

PDB Information

PDB	4QIA
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme. Charton, J., Gauriot, M., Totobenazara, J., Hennuyer, N., Dumont, J., Bosc, D., Marechal, X., Elbakali, J., Herledan, A., Wen, X., Ronco, C., Gras-Masse, H., Heninot, A., Pottiez, V., Landry, V., Staels, B., Liang, W.G., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R. Eur.J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-05-30
Resolution	3.200
CATH Insert Date	28 Jun, 2015

PDB Images (11)

Image of CATH 4qia

4qia

PDB 4qia

Image of CATH 4qiaA

4qiaA

PDB Chain 4qiaA

Image of CATH 4qiaB

4qiaB

PDB Chain 4qiaB

Image of CATH 4qiaA01

4qiaA01

CATH Domain 4qiaA01

Image of CATH 4qiaA02

4qiaA02

CATH Domain 4qiaA02

Image of CATH 4qiaA03

4qiaA03

CATH Domain 4qiaA03

Image of CATH 4qiaA04

4qiaA04

CATH Domain 4qiaA04

Image of CATH 4qiaB01

4qiaB01

CATH Domain 4qiaB01

Image of CATH 4qiaB02

4qiaB02

CATH Domain 4qiaB02

Image of CATH 4qiaB03

4qiaB03

CATH Domain 4qiaB03

Image of CATH 4qiaB04

4qiaB04

CATH Domain 4qiaB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4qiaA01	10 Jul, 2015	3.30.830.10	Assigned
4qiaA02	10 Jul, 2015	3.30.830.10	Assigned
4qiaA03	10 Jul, 2015	3.30.830.10	Assigned
4qiaA04	10 Jul, 2015	3.30.830.10	Assigned
4qiaB01	10 Jul, 2015	3.30.830.10	Assigned
4qiaB02	10 Jul, 2015	3.30.830.10	Assigned
4qiaB03	10 Jul, 2015	3.30.830.10	Assigned
4qiaB04	10 Jul, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme