PDB 4q1n

PDB Information

PDB4Q1N
MethodX-RAY DIFFRACTION
Host OrganismHomo Sapiens
Gene SourceHomo sapiens
Primary Citation
Structure-based design of substituted piperidines as a new class of highly efficacious oral direct Renin inhibitors.
Ehara, T., Irie, O., Kosaka, T., Kanazawa, T., Breitenstein, W., Grosche, P., Ostermann, N., Suzuki, M., Kawakami, S., Konishi, K., Hitomi, Y., Toyao, A., Gunji, H., Cumin, F., Schiering, N., Wagner, T., Rigel, D.F., Webb, R.L., Maibaum, J., Yokokawa, F.
ACS Med Chem Lett
HeaderHydrolase/Hydrolase Inhibitor
Released2014-04-04
Resolution2.090
CATH Insert Date24 Aug, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4q1nA01 27 Aug, 2014 2.40.70.10 Assigned
4q1nA02 27 Aug, 2014 2.40.70.10 Assigned
4q1nB01 27 Aug, 2014 2.40.70.10 Assigned
4q1nB02 27 Aug, 2014 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin