PDB 4pqn

PDB Information

PDB4PQN
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Property- and structure-guided discovery of a tetrahydroindazole series of interleukin-2 inducible T-cell kinase inhibitors.
Burch, J.D., Lau, K., Barker, J.J., Brookfield, F., Chen, Y., Chen, Y., Eigenbrot, C., Ellebrandt, C., Ismaili, M.H., Johnson, A., Kordt, D., MacKinnon, C.H., McEwan, P.A., Ortwine, D.F., Stein, D.B., Wang, X., Winkler, D., Yuen, P.W., Zhang, Y., Zarrin, A.A., Pei, Z.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-03-03
Resolution1.710
CATH Insert Date20 Jul, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4pqnA01 27 Jul, 2014 3.30.200.20 Assigned
4pqnA02 27 Jul, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK