PDB 4pp7

PDB Links
Overview

PDB Information

PDB	4PP7
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase. Wenglowsky, S., Ren, L., Grina, J., Hansen, J.D., Laird, E.R., Moreno, D., Dinkel, V., Gloor, S.L., Hastings, G., Rana, S., Rasor, K., Sturgis, H.L., Voegtli, W.C., Vigers, G., Willis, B., Mathieu, S., Rudolph, J. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2014-02-26
Resolution	3.400
CATH Insert Date	13 Apr, 2014

PDB Images (7)

Image of CATH 4pp7

4pp7

PDB 4pp7

Image of CATH 4pp7A

4pp7A

PDB Chain 4pp7A

Image of CATH 4pp7B

4pp7B

PDB Chain 4pp7B

Image of CATH 4pp7A01

4pp7A01

CATH Domain 4pp7A01

Image of CATH 4pp7A02

4pp7A02

CATH Domain 4pp7A02

Image of CATH 4pp7B01

4pp7B01

CATH Domain 4pp7B01

Image of CATH 4pp7B02

4pp7B02

CATH Domain 4pp7B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Apr, 2014	Chopped
B	14 Apr, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4pp7A01	17 Apr, 2014	3.30.200.20	Assigned
4pp7A02	17 Apr, 2014	1.10.510.10	Assigned
4pp7B01	25 Apr, 2014	3.30.200.20	Assigned
4pp7B02	25 Apr, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf