PDB 4pjt

PDB Information

PDB4PJT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural basis for the inhibition of poly(ADP-ribose) polymerases 1 and 2 by BMN 673, a potent inhibitor derived from dihydropyridophthalazinone.
Aoyagi-Scharber, M., Gardberg, A.S., Yip, B.K., Wang, B., Shen, Y., Fitzpatrick, P.A.
Acta Crystallogr.,Sect.F
HeaderTransferase/Transferase Inhibitor
Released2014-05-12
Resolution2.350
CATH Insert Date05 Oct, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 06 Oct, 2014 Chopped
B 06 Oct, 2014 Chopped
C 06 Oct, 2014 Chopped
D 06 Oct, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4pjtA01 08 Oct, 2014 1.20.142.10 Assigned
4pjtA02 08 Oct, 2014 3.90.228.10 Assigned
4pjtB01 08 Oct, 2014 1.20.142.10 Assigned
4pjtB02 08 Oct, 2014 3.90.228.10 Assigned
4pjtC01 08 Oct, 2014 1.20.142.10 Assigned
4pjtC02 08 Oct, 2014 3.90.228.10 Assigned
4pjtD01 08 Oct, 2014 1.20.142.10 Assigned
4pjtD02 08 Oct, 2014 3.90.228.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1
P09874 PARP1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase 1