PDB 4pf9

PDB Information

PDB4PF9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.
Durham, T.B., Toth, J.L., Klimkowski, V.J., Cao, J.X., Siesky, A.M., Alexander-Chacko, J., Wu, G.Y., Dixon, J.T., McGee, J.E., Wang, Y., Guo, S.Y., Cavitt, R.N., Schindler, J., Thibodeaux, S.J., Calvert, N.A., Coghlan, M.J., Sindelar, D.K., Christe, M., Kiselyov, V.V., Michael, M.D., Sloop, K.W.
J.Biol.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-04-28
Resolution2.500
CATH Insert Date28 Jun, 2015

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4pf9A01 10 Jul, 2015 3.30.830.10 Assigned
4pf9A02 10 Jul, 2015 3.30.830.10 Assigned
4pf9A03 10 Jul, 2015 3.30.830.10 Assigned
4pf9A04 10 Jul, 2015 3.30.830.10 Assigned
4pf9B01 10 Jul, 2015 3.30.830.10 Assigned
4pf9B02 10 Jul, 2015 3.30.830.10 Assigned
4pf9B03 10 Jul, 2015 3.30.830.10 Assigned
4pf9B04 10 Jul, 2015 3.30.830.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme
P14735 IDE_HUMAN Homo sapiens Insulin-degrading enzyme