PDB 4pf7

PDB Links
Overview

PDB Information

PDB	4PF7
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo. Durham, T.B., Toth, J.L., Klimkowski, V.J., Cao, J.X., Siesky, A.M., Alexander-Chacko, J., Wu, G.Y., Dixon, J.T., McGee, J.E., Wang, Y., Guo, S.Y., Cavitt, R.N., Schindler, J., Thibodeaux, S.J., Calvert, N.A., Coghlan, M.J., Sindelar, D.K., Christe, M., Kiselyov, V.V., Michael, M.D., Sloop, K.W. J.Biol.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-04-28
Resolution	2.330
CATH Insert Date	28 Jun, 2015

PDB Images (11)

Image of CATH 4pf7

4pf7

PDB 4pf7

Image of CATH 4pf7A

4pf7A

PDB Chain 4pf7A

Image of CATH 4pf7B

4pf7B

PDB Chain 4pf7B

Image of CATH 4pf7A01

4pf7A01

CATH Domain 4pf7A01

Image of CATH 4pf7A02

4pf7A02

CATH Domain 4pf7A02

Image of CATH 4pf7A03

4pf7A03

CATH Domain 4pf7A03

Image of CATH 4pf7A04

4pf7A04

CATH Domain 4pf7A04

Image of CATH 4pf7B01

4pf7B01

CATH Domain 4pf7B01

Image of CATH 4pf7B02

4pf7B02

CATH Domain 4pf7B02

Image of CATH 4pf7B03

4pf7B03

CATH Domain 4pf7B03

Image of CATH 4pf7B04

4pf7B04

CATH Domain 4pf7B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4pf7A01	10 Jul, 2015	3.30.830.10	Assigned
4pf7A02	10 Jul, 2015	3.30.830.10	Assigned
4pf7A03	10 Jul, 2015	3.30.830.10	Assigned
4pf7A04	10 Jul, 2015	3.30.830.10	Assigned
4pf7B01	10 Jul, 2015	3.30.830.10	Assigned
4pf7B02	10 Jul, 2015	3.30.830.10	Assigned
4pf7B03	10 Jul, 2015	3.30.830.10	Assigned
4pf7B04	10 Jul, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme