PDB Information

PDB4P8N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceMycobacterium tuberculosis
Primary Citation
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1.
Neres, J., Hartkoorn, R.C., Chiarelli, L.R., Gadupudi, R., Pasca, M.R., Mori, G., Venturelli, A., Savina, S., Makarov, V., Kolly, G.S., Molteni, E., Binda, C., Dhar, N., Ferrari, S., Brodin, P., Delorme, V., Landry, V., de Jesus Lopes Ribeiro, A.L., Farina, D., Saxena, P., Pojer, F., Carta, A., Luciani, R., Porta, A., Zanoni, G., De Rossi, E., Costi, M.P., Riccardi, G., Cole, S.T.
Acs Chem.Biol.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2014-03-31
Resolution1.790
CATH Insert Date21 Dec, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Dec, 2014 Chopped
B 22 Dec, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4p8nA00 29 Dec, 2014 Holding pen
4p8nB00 29 Dec, 2014 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P9WJF1 DPRE1_MYCTU Mycobacterium tuberculosis H37Rv Decaprenylphosphoryl-beta-D-ribose oxidase
P9WJF1 DPRE1_MYCTU Mycobacterium tuberculosis H37Rv Decaprenylphosphoryl-beta-D-ribose oxidase