PDB 4p38
PDB Information
| PDB | 4P38 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Novel acidic 11 beta-hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) inhibitor with reduced acyl glucuronide liability: the discovery of 4-[4-(2-adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic acid (AZD8329).
J.Med.Chem.
|
| Header | Oxidoreductase/Oxidoreductase Inhibitor |
| Released | 2014-03-06 |
| Resolution | 2.800 |
| CATH Insert Date | 04 May, 2014 |
PDB Prints
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 05 May, 2014 | Chopped |
| B | 05 May, 2014 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4p38A00 | 08 May, 2014 | 3.40.50.720 | Assigned |
| 4p38B00 | 09 May, 2014 | 3.40.50.720 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P28845 | DHI1_HUMAN | Homo sapiens | Corticosteroid 11-beta-dehydrogenase isozyme 1 |
| P28845 | DHI1_HUMAN | Homo sapiens | Corticosteroid 11-beta-dehydrogenase isozyme 1 |
