PDB 4ov6

PDB Information

PDB4OV6
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering.
Mitchell, T., Chao, G., Sitkoff, D., Lo, F., Monshizadegan, H., Meyers, D., Low, S., Russo, K., DiBella, R., Denhez, F., Gao, M., Myers, J., Duke, G., Witmer, M., Miao, B., Ho, S.P., Khan, J., Parker, R.A.
J.Pharmacol.Exp.Ther.
HeaderHydrolase/Protein Binding
Released2014-02-20
Resolution2.690
CATH Insert Date20 Jul, 2014

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 21 Jul, 2014 Chopped
B 21 Jul, 2014 Chopped
D 21 Jul, 2014 Chopped
E 21 Jul, 2014 Chopped
F 21 Jul, 2014 Chopped
G 21 Jul, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ov6A01 03 Aug, 2014 3.30.70.80 Assigned
4ov6B00 03 Aug, 2014 3.40.50.200 Assigned
4ov6D01 27 Jul, 2014 3.30.70.80 Assigned
4ov6E00 27 Jul, 2014 3.40.50.200 Assigned
4ov6F00 03 Aug, 2014 2.60.40.10 Assigned
4ov6G00 27 Jul, 2014 2.60.40.10 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
A0A075B5G3 A0A075B5G3_HUMAN Homo sapiens Adnectin
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
A0A075B5G3 A0A075B5G3_HUMAN Homo sapiens Adnectin
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9
Q8NBP7 PCSK9_HUMAN Homo sapiens Proprotein convertase subtilisin/kexin type 9