PDB 4ot6

PDB Information

PDB4OT6
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-Based Drug Design of RN486, a Potent and Selective Bruton's Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis.
Lou, Y., Han, X., Kuglstatter, A., Kondru, R.K., Sweeney, Z.K., Soth, M., McIntosh, J., Litman, R., Suh, J., Kocer, B., Davis, D., Park, J., Frauchiger, S., Dewdney, N., Zecic, H., Taygerly, J.P., Sarma, K., Hong, J., Hill, R.J., Gabriel, T., Goldstein, D.M., Owens, T.D.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-02-13
Resolution2.050
CATH Insert Date18 May, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 19 May, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ot6A01 21 May, 2014 3.30.200.20 Assigned
4ot6A02 21 May, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK